How's it going?
This phrase is asking about the other person's life (work or personal life).
How are you getting on?
This phrase is asking about the other person's life (work or personal life).
How have you been?
This phrase is really asking about health but the other person may answer with general information about their life.
What have you been (getting) up to?
This phrase is really asking about what kind of activities the other person has been doing recently, It more often refers to their home life, not work
I Hope everything's okay?
This phrase is asking about health and life with a yes / no question.
Alright? This phrase is asking about health and life with a yes / no question. It is much more informal than I hope everything is okay?
How have you been keeping?
This phrase is more formal but still sincere and friendly and is asking about the other person's health.

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